• Company:
    J&J Family of Companies
  • Location:
  • Salary:
    negotiable / month
  • Job type:
  • Posted:
    9 hours ago
  • Category:

Senior Scientific Director Investigative

Janssen Research & Development, L.L.C., a
division of Johnson & Johnson’s Family of Companies is recruiting an
Investigative Toxicology Leader (Senior Director) located in San Diego.

At the Janssen Pharmaceutical Companies of
Johnson & Johnson, we are working to create a world without disease.
Transforming lives by finding new and better ways to prevent, intercept, treat
and cure disease inspires us. We bring together the best minds and pursue the
most promising science. We are Janssen. We collaborate with the world for the
health of everyone in it. Learn more at and follow us
@JanssenGlobal. Janssen Research &
Development, LLC is part of the Janssen Pharmaceutical Companies.

The Senior Director, Global Head Investigative
Toxicology, Nonclinical Safety (NCS) will be responsible for defining and
executing the de-risking strategy for all novel therapeutics across multiple
therapeutic areas and modalities.

The successful candidate will establish and manage
state of the art scientific and laboratory capabilities within Nonclinical
Safety. He/she will coordinate the early safety derisking pipeline and develop
rapid issue resolution capabilities, deploying cutting-edge approaches in cell
biology, biochemistry, molecular profiling & systems toxicology, and
investigative in vivo models to identify, understand, and assess safety issues.

He/she will partner with Project Toxicologists
to provide strategic and scientific input to multidisciplinary Project Teams
across the pipeline from discovery through post-registration with an emphasis
on molecule/target discovery and prioritization, and issue resolution.

This leader will be expected to cooperate
closely with colleagues in computational toxicology and other functions across
preclinical safety in the US and Europe, and employ both internal and external
(Contract Research Organization) resources and expertise pragmatically to
efficiently deliver comprehensive, data-driven molecule and target selection
and human risk assessment, and to inform internal decision-making globally.

Overseeing a team of PhD level and technical
level staff, the Senior Director will provide leadership, mentorship, and
career development opportunities for his/her global team. This role will be
responsible for future capital planning, innovation strategy, budget, resource
and timeline commitments for the group.

The Senior Director, Global Head of
Investigative Toxicology will join the Extended Nonclinical Safety Senior
Leadership Team and will serve as needed as delegate leadership to early
portfolio governance and in evaluation of due diligence opportunities. He/she will also be a member of the Extended Nonclinical Safety Leadership team responsible for
the review and approval of nonclinical safety strategies as well as major issue
review and recommendations for resolution.

The Senior Director will have a desire for
learning and innovation, and continue career development through participation
in scientific meetings, and increase visibility for self, Janssen R&D, and
J&J, through publications, participation in external organizations, and
presentations at major scientific, industry, and regulatory meetings. 20% national and international travel is



Ph.D. in biochemistry, biophysics, cell
biology, genetics, molecular biology, pharmacology, toxicology or related
discipline (bioengineering, medicine, veterinary science or related field)
and/or professional degree (DVM, VMD) with training or extensive experience in
cell and molecular toxicology or related biologic disciplines

15 + years of pharmaceutical/biotechnology
research management or related experience in drug development

Proven track-record in leading complex
scientific and laboratory teams, including direct people management and
laboratory management experience across geographies

Exceptional diplomacy and negotiating skills

This role requires excellent communication and
interpersonal skills, a high level of organizational ability and attention to

Good communication skills, attention to
detail, troubleshooting skills and ability to work effectively in a
collaborative environment

Strong scientific and technical skills in
emerging cellular and biochemical toxicology, target organ in vitro models, and
animal alternative assays as well as ability to propose mechanistic hypotheses,
design and oversee the execution of experiments

Primary Location

United States-Pennsylvania-Spring House-1400�McKean�Road

Other Locations

Belgium-Antwerp-Beerse, United States-California-La Jolla


Janssen Research & Development, LLC (6084)

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